My "Kane Edition" copy of Command & Conquer 3 arrived today, and as soon as the kids were down I fired it up and took it for a spin. Command & Conquer was probably the first RTS I got seriously into (though Dune 2 was certainly in there as well), and I have very fond memories of the franchise. The cheezy full motion video sequences are a big plus for me, and C&C 3 doesn't disappoint in that category so far. Sure, you won't be seeing King Lear but they perfectly capture the C&C vibe.
The game is quite attractive, and the core gameplay is frenetic. They have some very nice touches, like an in-game database and some nice unit control & queueing UI conventions. I did try my hand at one multiplayer game only to realize how badly out of practice I am... but I look forward to a lot more evenings with C&C 3. In fact, the only thing that might stop me is trying to leave some content untouched for when the 360 version comes out...