The raid alliance that I play with on Earthen Ring (SASU) has downed Nefarian! It was a lot of fun, and is probably one of my favorite boss fights in World of Warcraft. This was our 3rd week of getting to Nefarian, and only our second week of reliably getting him into his dragon form. Amazingly we dropped him on our second try tonight, and came very close to getting him on the first! Sometimes things are just firing on all cylinders.
I have a number of complaints with the game design of the 40 man raids, and the over-emphasis that Blizzard has put on them in the game. But I do have to say, it's a rush to finally topple one of the end-game bosses like that for the first time...